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Phacoemulsification
(Phacoemulsification cataractsurgery)
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Introduction
  • Phacoemulsification cataract surgery describes the breakdown and removal of a cataract by high frequency ultrasound.
  • The ultrasonic waves are generated within a handpiece connected to a phacoemulsification unit. The handpiece is inserted into the cataractous lens via a small corneal incision and a circular incision within the anterior lens capsule.
  • During the phacoemulsification procedure, fluid irrigation and aspiration is used to maintain the shape of the globe, to keep the tip of the handpiece cool and to remove the lens fragments.

Uses
  • For removal of cataracts Cataract  Cataract: acquired  Lens: congenital primary cataract  Lens: hereditary primary cataract.
  • For removal of a subluxated lens Lens luxation.
  • For treatment of acute traumatic lens capsule rupture leading to phacoclastic uveitis Uveitis.

Advantages
  • Phacoemulsification is a state-of-the-art technique which, in experienced hands, offers the best success rate for cataract surgery in dogs and cats.
  • Following removal of the cataract, the lens capsule remains in place and an artificial intra-ocular lens (IOL) can be placed within the capsule to optimize visual acuity.
  • Bilateral cataract surgery can be performed under the same anesthetic.
  • When used for treatment of lens subluxation it gives a superior postoperative outcome to lendectomy (ICLE) Lendectomy.
  • Lens capsule rupture often leads to severe and intractable complications such as uveitis and secondary glaucoma Glaucoma. Early phacoemulsification surgery is often successful in preventing these complications and saving vision.

Disadvantages
  • Phacoemulsification is a specialist surgical technique. It is essential that the surgeon has extensive microsurgical experience and has undergone detailed training in phacoemulsification techniques.
  • The use of an operating microscope and the correct microsurgical instrumentation and consumables are essential.
    Referral to a specialist ophthalmologist who is experienced in this technique is required.
  • Owner and patient compliance are vital. Intensive post-operative topical and systemic medications are essential for the success of this procedure, and regular post-operative re-examinations are required.
  • Postoperative complications may include wound breakdown, corneal ulceration Persistent corneal erosions , anterior uveitis, secondary glaucoma, retinal detachment Retina: detachment.


Alternative techniques
  • Extracapsular cataract extraction (ECCE). This technique has been superseded by phacoemulsification.

Procedure
  • 30-40 minutes per eye for an experienced surgeon.


Decision taking

Risk assessment
  • Phacoemulsification can be performed on all stages of cataract, but there is a higher risk of complications in advanced (hypermature) cataracts, and some cataracts may become inoperable due to complications such as retinal detachment, severe uveitis or secondary glaucoma.
  • Following a diagnosis of cataract, early referral to a veterinary ophthalmologist is advised, so that the surgical suitability can be assessed. This is especially important in the case of diabetic cataracts, which can progress rapidly to become inoperable.
  • Owner and patient compliance are vital. Intensive post-operative topical and systemic medications are essential for the success of this procedure, and regular post-operative re-examinations are required.
Requirements Top
Personnel
Veterinarian expertise
  • Referral to a veterinary ophthalmologist with extensive experience performing phacoemulsification cataract surgery is essential.

Anesthetist expertise
  • Neuromuscular blockade Anesthesia: non-depolarizing neuromuscular blockade can be used to centralize the globe and so aid surgery. Experience of neuromuscular blockade and anesthesia is essential if using this technique.

Nursing expertise
  • For intra-operative assistance and post-operative medication.


Materials required
Minimum equipment
  • Operating microscope.
  • Operating chair.
  • Phacoemulsification unit and handpiece.
  • Intra-ocular microsurgical kit suitable for phacoemulsification.
  • Artificial intra-ocular lens (IOL).
  • Lens inserter for foldable IOL.
  • Fluids, tubing and phacoemulsification consumables.
Preparation Top

Dietary preparation
  • Fast patient for 12 hours prior to anesthesia.

Site preparation
  • Sterile preparation of peri-ocular skin and flushing of conjunctival sac and ocular surface with dilute povidone-iodine solution Povidone-iodine  (0.2%) and eyewash.
  • Lateral canthotomy Canthotomy , may be performed prior to corneal incision, to improve surgical access.
Procedure Top
Approach

Step 1 - Bimanual technique - preparation
  • Position head with corneal surface positioned horizontally beneath operating microscope.
  • Aseptically prepare and drape the eye for surgery.
  • Place eyelid retractors.

Step 2 - Perform lateral canthotomy
  • Perform lateral canthotomy to increase exposure of globe if indicated.
  • Use perilimbal stay sutures and mosquito forceps to aid positioning of globe (if not using neuromuscular blockade).

Step 3 - Make 2 mm incision
  • Perform penetrating 2 mm incision with corneal stab knife (side port incision).


Step 4 - Inject viscoelastic material
  • Inject viscoelastic material (hydroxypropylmethylcellulose and hyaluronic acid) to maintain inflation of anterior chamber and to protect the corneal endothelium and intra-ocular structures.

Step 5 - Make 3 mm incision
  • Perform penetrating 3 mm incision with keratome, positioned 45°-60° from side port incision at dorsal aspect of globe.
  • Create a circular anterior lens capsule incision (anterior capsulorrhexis) to remove the central portion of the anterior lens capsule and allow access to the lens itself.
  • Hydrodissection of cataract to separate lens cortex from capsule.

Core Procedure

Step 1 - Phacoemulsification
  • Phacoemulsification of lens nucleus and cataractous cortex by preferred technique (eg ‘divide and conquer’, ‘phaco chop’), using the ultrasonic handpiece inserted through the perilimbal incision Phacoemulsification 01  Phacoemulsification 02.


Step 2 - Irrigation/aspiration
  • Irrigation/aspiration to remove cortical fragments Phacoemulsification 03.
  • Capsule polishing.


Step 3 - Extend primary incision
  • Extend primary (dorsal) corneal incision by a few millimeters.
  • Place IOL into remaining lens capsule bag (through extended incision) Phacoemulsification 04  Phacoemulsification 05.

Exit
Step 1 - Closure
  • The corneal incision is closed using 8-0 or 9-0 Vicryl.
  • Repair lateral canthotomy wound using 4/0 or 5/0 nylon.
Aftercare Top
Immediate Aftercare

Analgesia
  • Carprofen Carprofen or meloxicam Meloxicam at standard dose, given pre-operatively and continued post-operatively for 7 days or longer if indicated.

Antimicrobial therapy
  • Systemic antimicrobials (eg cephalosporins) for 7 days.

Other medication
  • Chloramphenicol Chloramphenicol  (or other prophylactic antibiotic) drops TID for 7 days.
  • Prednisolone acetate Prednisolone 1% at gradually reducing dose (initially TID to QID).
  • Mydriatics (tropicamide Tropicamide or atropine Atropine ) as needed to combat intra-ocular inflammation and maintain pupil mobility.

Wound Protection
  • Foot bandage or head collar.

Potential complications
  • Post-operative: wound breakdown, corneal ulceration, anterior uveitis, secondary glaucoma, retinal detachment.


Long term Aftercare

Follow up
  • Regular re-examinations are recommended to check for complications. In the short-term, weekly check-ups are advisable for the first few weeks following surgery. In the long-term, regular check-ups (eg 3 monthly) are recommended, and should include intra-ocular pressure measurements.
  • Anti-glaucoma medications should be instigated if the intra-ocular pressure becomes elevated.
Sequelae Top
Sources Top

Publications
Refereed papers
  • Recent references from PubMed.

Other sources of information
  • Wilkie D A, Colitz C M H (2007) Surgery of the canine lens. In: Veterinary Ophthalmologyfourth edition. Ed. K N Gelatt. Blackwell Publishing, Iowa, USA, pp 888-931.


Vetstream contributor(s)
  • Alison B Clode DVM DACVO , North Carolina State University, College of Veterinary Medicine, 4700 Hillsborough Street, Raleigh NC 27606, USA.
  • David Gould BSc (Hons) BVM&S PhD DVOphthal DipECVO MRCVS , Davies Veterinary Specialists, Manor Farm Business Park, Higham Gobion, Hitchin, Hertfordshire SG5 3HR, UK.

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Anesthesia: non-depolarizing neuromuscular blockade
Atropine
Canthotomy
Carprofen
Cataract
Cataract: acquired
Chloramphenicol
Glaucoma
Lendectomy
Lens luxation
Lens: congenital primary cataract
Lens: hereditary primary cataract
Meloxicam
Persistent corneal erosions
Povidone-iodine
Prednisolone
Retina: detachment
Tropicamide
Uveitis
Phacoemulsification 01 Phacoemulsification 02
Phacoemulsification 03 Phacoemulsification 04
Phacoemulsification 05
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