Vetstream header image and menu Click for a free trial
Phenylpropanolamine / diphenylpyraline
 Feedback

Name
  • Phenylpropanolamine.

Class of drug
  • Sympathomimetic amine (alpha agonist).

Description

Chemical name
  • 4-(diphenylmethoxy)-1-methylpiperidine.

Molecular formula
  • C19H23NO.

Physical properties
  • Clear liquid.

Storage requirements
  • <25°C.
  • In a dry environment.
  • Do not store in fridge.
Uses Top

Action
  • A sympathomimetic amine which stimulates alpha adrenergic receptors.
  • In the lower urinary tract, increases urethral outflow resistance.
  • Peripheral vasoconstrictive qualities.

Indications
  • Management of lower urinary tract incontinence Urinary incontinence by increasing urethral outflow resistance.
  • Management of nasal congestion.
Administration Top

Routes of administration
  • Capsule.
  • Tablets.

Dosage

Basic dose


Dogs and cats
  • 1-1.5 mg/kg PO BID-TID.

Timing of administration
  • Onset of action may take several days.
Pharmocokinetics Top
Precautions Top
Adverse reactions Top

Other reported reactions
  • Restlessness.
  • Irritability.
  • Hypertension.
  • Aggression.
Sources Top

Publications

Refereed papers
  • Scott L, Leddy M, Bernay F and Davot J L (2002) Evaluation of phenylpropanolamine in the treatment of urethral sphincter mechanism incompetence in the bitch. JSAP 43 , 493-496PubMed.

Other sources of information
  • Based on Small Animal Formulary. Tennant, Bryn (1999) 3rd edn. Cheltenham: BSAVA.

Vetstream contributor(s)
  • Dr Lauren Trepanier , Department of Medical Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, 2015 Linden Drive West, Madison, WI 53706-1102, USA.
Back to top
© Copyright Vetstream

CANIS GEN00222
















































































Subscribers and trialists can view the additional links below and within theadjacent article. To trial our services click here:
Colposuspension for urinary incontinence
Esmolol
Pelvic bladder
Propalin Syrup
Therapeutics: urinary system
Transection and reimplantation: ureter
Ureter: ectopic
Urinary incontinence (USMI)
Urinary incontinence
Please click on the links below to view this months other FOC content:
Click to subscribe
Copyright © Vetstream  Terms and Conditions  Privacy policy